Normaytancyprine, A Minor Antileukemic Ansa Macrolide From Putterlickia verrucosa

Journal of Natural Products
1982.0

Abstract

Normaytancyprine (2), a new minor antileukemic maytansinoid, was isolated from Putterlickia verrucosa Szyseyl. The structure was elucidated by a chemical interconversion to normaysine and by 'H and 13C nmr and mass spectrometry. Normaytancyprine was found to contain an unusual dimethylcyclopropylcarboxyl moiety in the C-3 amino acid ester.

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