Antitumor Principles in Mosses: the First Isolation and Identification of Maytansinoids, Including a Novel 15-Methoxyansamitocin P-3

Journal of Natural Products
1988.0

Abstract

A novel 15-methoxyansamitocin P-3 [2], in company with three known maytansinoids 1, 3, and 4, was isolated for the first time from two Japanese mosses, Isothecium subdiversiforme and Thamnobryum sandei. All are potent cytotoxic compounds.

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