Novel Cytotoxic Thiodiketopiperazine Derivatives from a Tilachlidium sp.

Journal of Natural Products
2004.0

Abstract

Three novel thiodiketopiperazine derivatives, T988 A, B, and C (1-3), were isolated from a Tilachlidium sp. Their structures were elucidated by spectroscopic analyses using various 1D and 2D NMR techniques. All the compounds showed potent cytotoxicity against cultured P388 leukemia cells.

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