Multi Receptor Targeting of Potential Bioactive Compound Obtained from Chloroform Extract of Asparagus racemosus by GC-MS Analysis: A in silico Based Approach

Asian Journal of Chemistry
2024.0

Abstract

Previous reports indicate that the medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of therapeutic possibilities. This study aimed to underscores the potential bioactive compounds found within the chloroform extract of Asparagus racemosus. Gas-chromatography employed to identify the presence of various molecules, while mass spectrometry and FTIR analysis validated their molecular structures. The molecules were analyzed to assess its suitability as a therapeutic candidate, their biological activity and predicted targets using in silico techniques. The chloroform extract stands out as the richest reservoir of carbohydrates and steroidal alkaloids. Molecule (5β)-pregnane-3,20β-diol, 14α,18α-[4-methyl-3-oxo-(1-oxa-4-azabutane-1,4-diyl)]diacetate was found in the highest concentration (42.28 %). The identified molecule is a steroidal alkaloid in nature and the computational analysis revealed promising drug-like properties and therapeutic potential for the investigated molecule. © 2024 Asian Publication Corporation. All rights reserved.

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