The phytochemical composition of Ficus tikoua Bur. was studied, from which fourteen compounds were isolated, including four phenolics (1-4), 1- 4 ), one aromatic alcohol glycoside (5), 5 ), two benzofuran derivatives (6-7), 6 - 7 ), five sesquiterpenes (8-12), 8 - 12 ), one lignan (13) 13 ) and one alkaloid (14). 14 ). The structures of these compounds were determined by MS, NMR spectroscopy, and comparison with the published spectroscopic data. Compounds 1 - 3 , 5 , and 7-14 - 14 were firstly isolated from F. tikoua , , and compounds 1, 5, 10, 11, 13 and 14 were reported from genus Ficus for the first time. Furthermore, the research discussed the taxonomic significance of the isolated compounds, and enriched the knowledge of the chemical classification of genus Ficus. .