Synthesis and Structure of Alkyl Derivatives of Convolvine

Chemistry of Natural Compounds
2023.0

Abstract

Alkyl derivatives of the tropane alkaloid convolvine (3,4-dimethoxybenzoyloxynortropane) were synthesized via reactions with a series of alkyl halides. The structures of the synthesized compounds were proven using IR and NMR spectroscopy. X-ray crystal structure analyses established the molecular structures of the hydrochlorides of the N-hexyl-, N-octyl-, and N-nonyl-derivatives of convolvine.

DOI： 10.1007/s10600-023-03930-y

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