Ten new monoterpenoid indole alkaloids, ochroborines A and B (1 and 2, resp.), 10-hydroxyisovallesiachotamine (3), 10-hydroxyisositsirikine (4), 10,11-dimethoxysitsirikine (5), 10-methoxyapoyohimbine (6), 10- hydroxyakuammidine (7), akuammidine 17-O-β-D-glucoside (8), 15α-hydroxyapparicine (9), and 15α-hydroxy-10-methoxyapparicine (10), and 24 known alkaloids were isolated from leaves and twigs of Ochrosia borbonica J. F.Gmel. These structures were elucidated based on 1D- and 2D-NMR, FT-IR, UV, and MS data. 10-Hydroxyisovallesiachotamine (3), ellipticine, and 10-methoxyellipticine showed cytotoxic activities against five human cancer cell lines. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.