Two novel dimeric pyrrole-aminoimidazole (PAI) alkaloids (-) donnazoles A-B (1-2) were isolated from the marine sponge Axinella donnani collected off the Mauritius Island. Their structures were elucidated mainly by 2D NMR. Both compounds bear the crucial substituted cyclopentane of 'pre-axinellamine', the hypothetical common intermediate of all dimeric PAIs. Additionally, the essential trans-6,7 ring junction of palau′amine's congeners is already established in 1 and 2. The absolute configurations of 1 and 2 were deduced via NOE correlations in combination with the comparison of their circular dichroism data with the one of (-) sceptrin. The absolute configuration of (-) donnazoles A (1) and B (2) is coherent with the absolute configuration of the known dimeric members of PAI alkaloids. © 2012 Elsevier Ltd. All rights reserved.