Indolalkaloide aus Kopsia dasyrachis Ridl. 185.Mitteilung über organische Naturstoffe

Helvetica Chimica Acta
1982.0

Abstract

Indole Alkaloids of Kopsia dasyrachis Ridl. From the leaves of Kopsia dasyrachis Ridl. three new indole alkaloids, kopsidasine‐N‐oxide (1), kopsidasine (2) and kopsidasinine (3) have been isolated. Reduction of 1 with SO2 afforded 2; treatment of 2 with m‐chloroperbenzoic acid gave 1. The structure elucidation of 1 and 2, and the deternmination of their relative configurations are based mainly on the correlation of derivative 6 with the known ring skeleton of pleiocarpine (9) (Scheme 1). The structure of 3 has been established via its Hofmann degradation product 13 also prepared by treatment of 2 with CH3I (Scheme 3). Copyright © 1982 Verlag GmbH & Co. KGaA, Weinheim

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