Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells

Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells K-252a, a potent inhibitor of protein kinase C from microbial origin. Neurotrophic 3,9-Bis[(alkylthio)methyl]- and -Bis(alkoxymethyl)-K-252a Derivatives Indocarbazostatin, a Novel Inhibitor of NGF-induced Neurite Outgrowth from Rat Pheochromocytoma PC12 Cells. Synthesis and kinase inhibitory activity of 3′-(S)-epi-K-252a Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells. I. Screening, Taxonomy, Fermentation and Biological Activities. The Shurosporine Producing Strain Streptomyces longisporoflavus Produces Metabolites Related to K-252a. Proposal for Biosynthetic Intermediates of K-252a. The structures of the novel protein kinase C inhibitors K-252a, b, c and d. Scabronine M, a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells from the fungus Sarcodon scabrosus Nerfilin I, a Novel Microbial Metabolite Inducing Neurite Outgrowth of PC12 Cells.