Two novel diglycosylated steroidal alkaloids of 5 delta-pregnene nucleus, named obtusine-20(R)-O-[beta-thevetopyranosyl-(1-->4)-beta-cyma ropyranoside] and obtusolactam-20(R)-O-[beta-thevetopyranosyl-(1-->4)-beta- cymaropyranoside], together with the known beta-sitosteryl-3-O-beta-glucopyranoside were isolated from the roots of Cryptolepis obtusa N. E. Br.