Literature

Abstract

Novel heterocyclic alkaloids (4 and 6), potential synthetic precursors of 20(S)-camptothecin (2), are synthesized by 2,3-dichloro-5,6-dicyanobenzoquinone oxidation of tetraacetyl-18,19-dihydrovincoside (18,19-H2-1a) and -iso-vincoside (18,19-H2-1c) lactams and their corresponding pentaacetyl-18,19-dihydroquinolols (18,19-H2-3). © 1976, American Chemical Society. All rights reserved.

DOI： 10.1021/jo00883a045

A biomimetic synthesis of the camptothecine chromophore

The Journal of Organic Chemistry 1976.0

Isolation and characterization of a presumed biosynthetic precursor of camptothecin from extracts of Camptotheca acuminata

Tetrahedron 1990.0

Discovering and harnessing oxidative enzymes for chemoenzymatic synthesis and diversification of anticancer camptothecin analogues

Communications Chemistry 2021.0

Camptothecins: Some Recent Chemical Studies

Natural Product Communications 2006.0

Plant antitumor agents. II. Structure of two new alkaloids from Camptotheca acuminata

The Journal of Organic Chemistry 1969.0

Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor