Three new alkaloids have been isolated from the leaves of Ochrosia alyxioides: 10-methoxycorynantheol [1], 10-methoxyantirhine [3], and 10-hydroxyantirhine [4]. Their structures have been established on the basis of their spectral data and chemical properties. In addition, seven known alkaloids have been isolated from the leaves and nine from the stem bark, which has also yielded 3. © 1989, American Chemical Society. All rights reserved.