Ten alkaloids have been isolated from the leaves of NEisosperma glomerata. Seven of them were identified as descarbomethoxydihydrogambirtannine (l), ochropposinine (2)' isoreserpiline (3), 10,11-dimethoxyajmalicine (4), tetraphylline (5)' tetraphyllinine (6) and tetraphylline oxindole-B (7). The three others are novel compounds: 11-methoxya-yohimbine (8), 11-methoxy-17epi-a-yohimbine (9) and 10,11-dimethoxy-l7-epia-yohimbine (13). Their structures have been established on the basis of their spectral data and chemical properties.