Rosmarinine, 12–0-acetylrosmarinine [6], neorosmarinine [3], hadiensine (lα-hydroxyplatyphylline) [2], 12–0-acetylhadiensine [4], 12–0-acetylneohadiensine {5], and petitianine (2α-hydroxy-l,2-dihydroretrorsine) [7} were isolated from Senecio hadiensis. The alkaloids 2–7 have not been described before. © 1991, American Chemical Society. All rights reserved.