A new alkaloid, 3,4,8-trimethoxy-2-quinolone [1], and six known compounds including two pyranocoumarins, avicennol and cis-avicennol, two dihydrocinnamic acid derivatives, eriostemoic acid and eriostoic acid, and two flavonoid glycosides, hesperidin and diosmin, have been isolated from the aerial parts of Eriostemon gardneri. © 1995, American Chemical Society. All rights reserved.