From the tubers of Arisarum vulgare, we have isolated two new toxic piperidinol alkaloids. By 2D COSY NMR spectroscopic methods, their structures were elucidated as follows:Irnigaine 3: (-)-(2S,3S,6R)-3-hydroxy-2-methyl-6-(9'-phenylnonyl)piperidine and N-methylirnigaine 4: (-)-(2S,3S,6R)-l,2-dimethyl-3-hydroxy-6-(9'-phenylnonyl) piperidine. © 1995, Taylor & Francis Group, LLC. All rights reserved.