A new type of lupin alkaloid, tsukushinamine (I) was isolated together with six known alkaloid, (—)-cytisine, (—)-rhombifoline, (—)-N-formylcytisine, ( —)~anagyrine, (-)- baptifoline and ( + )-ammodendrine, from the epigeal parts of Sophora franchetiana Dunn (Leguminosae). The structure of I was presumed to be a new type of tetracyclic lupin alkaloid by spectral data. © 1979, The Pharmaceutical Society of Japan. All rights reserved.