The structures of two new bis-indole alkaloids, 19’(R)-hydroxyconodurine (11) and 19’(R)-hydroxyconoduramine (12), from the leaves of Tabernaemontana subglobosa merr. (Apocynaceae), native to Taiwan, were determined by means of spectroscopic analysis and chemical reactions. © 1994, The Pharmaceutical Society of Japan. All rights reserved.