Preparation and evaluation of optically active 4,4-difluorothreonine as a potent novel antitumor material

Preparation and evaluation of optically active 4,4-difluorothreonine as a potent novel antitumor material Studies of antitumor agents. 1. Resolution of racemic 1-(tetrahydro-2-furanyl)-5-fluorouracil into the R and S isomers and examination of the biological activities of the isomers Studies on antitumor agents. 2. Syntheses and antitumor activities of 1-(tetrahydro-2-furanyl)-5-fluorouracil and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil Synthesis and antitumor activity of optically active thiourea and their 2-aminobenzothiazole derivatives: A novel class of anticancer agents Synthesis and in vivo antitumor activity of potential 5-fluorouracil prodrugs Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C 4a,9b-trans-8-Fluoro-5-(4-fluorophenyl)-2-[4-(4-fluorophenyl)-4-hydroxybutyl]-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole hydrochloride, a new potent neuroleptic Synthesis and Biological Activity of Folic Acid and Methotrexate Analogues Containing <scp>l</scp>-threo-(2S,4S)-4-Fluoroglutamic Acid and <scp>dl</scp>-3,3-Difluoroglutamic Acid Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048 Synthesis and antitumor activity of a series of ftorafur analogs: the effect of varying electronegativity at the 1'-position