Aryl phosphate derivates of AZT inhibit HIV replication in cells where the nucleoside is poorly active

Aryl phosphate derivates of AZT inhibit HIV replication in cells where the nucleoside is poorly active Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT Diaryl phosphate derivatives act as pro-drugs of AZT with reduced cytotoxicity compared to the parent nucleoside Uncharged AZT and D4T Derivatives of Phosphonoformic and Phosphonoacetic Acids as Anti-HIV Pronucleosides Aryl Phosphoramidate Derivatives of d4T Have Improved Anti-HIV Efficacy in Tissue Culture and May Act by the Generation of a Novel Intracellular Metabolite Aryl nucleoside H-phosphonates. Part 16: Synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters S-Acyl-2-Thioethyl Aryl Phosphotriester Derivatives of AZT:  Synthesis, Antiviral Activity, and Stability Study Phosphoramidate derivatives of d4T with improved anti-HIV efficacy retain full activity in thymidine kinase-deficient cells S-Acyl-2-thioethyl Aryl Phosphotriester Derivatives as Mononucleotide Prodrugs S-Acyl-2-thioethyl Phosphoramidate Diester Derivatives as Mononucleotide Prodrugs