Novel substituted indolocarbazoles as potent and selective inhibitors of protein kinase C

Bioorganic & Medicinal Chemistry Letters
1995.0

Abstract

Novel ollgopeptlde and amino alkyl substitued indolocarbazoles were synthesized and charactedzed with respect to Inhibition of protein klnases C and A. In both series potent and selective PKC inhibitore could be identified. Structure activity relationships are discussed.

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