Novel synthesis of nucleoside 5′-polyphosphates

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

We report a novel synthetic method to prepare nucleoside 5"-di- and triphosphates simultaneously. Their preparative separation and the possibilities to influence the product ratio were investigated. Preliminary results of the triphosphates to act as phosphate donors for the nucleoside diphosphate kinase (EC 2.7.4.6) are presented.

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