Synthesis and analgesic activity of Epibatidine analogues
Bioorganic & Medicinal Chemistry Letters
1996.0
Abstract
Two epibatidine analogues with different skeleton were synthesized and their analgesic activity was evaluated. Compound 2 which has the 8-azabicyclo[3.2.1]octane ring system showed potent analgesic activity in hot -plate assay.