The effect of fluorine substitution on the antimalarial activity of tebuquine

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

A novel synthetic mute has been developed for the synthesis of fluorotebuquine which was active against the chloroquine resistant KI strain of Plasmodium Falciparum, but less potent them both ehloroquine and tebuquine against the 3D7 strain.

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