Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene

Bioorganic & Medicinal Chemistry Letters
1998.0

Abstract

Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig reaction and Mitsunobu reaction as key steps and evaluated for antiviral activity.

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