Synthesis and biological evaluation of coumarincarboxylic acids as inhibitors of gyrase B. L-rhamnose as an effective substitute for L-noviose

Synthesis and biological evaluation of coumarincarboxylic acids as inhibitors of gyrase B. L-rhamnose as an effective substitute for L-noviose Structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B Improved antibacterial activities of coumarin antibiotics bearing 5′,5′-dialkylnoviose: biological activity of RU79115 Coumarin inhibitors of gyrase B with N -propargyloxy-carbamate as an effective pyrrole bioisostere Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B Synthesis and Evaluation of Noviose Replacements on Novobiocin That Manifest Antiproliferative Activity Biological Activities of Novel Gyrase Inhibitors of the Aminocoumarin Class Mannich reaction derivatives of novobiocin with modulated physiochemical properties and their antibacterial activities Cytotoxic sugar analogues of an optimized novobiocin scaffold Fine Tuning of physico-chemical parameters to optimise a new series of novobiocin analogues