Synthesis and antimicrobial activity of new 3α-Hydroxy-23,24-bisnorcholane polyamine carbamates

Bioorganic & Medicinal Chemistry Letters
2001.0

Abstract

3 alpha-Hydroxy-23,24-bisnorcholane spermidine and spermine carbamates 2-7 have been synthesized and their antimicrobial and hemolytic activities were evaluated. They exhibited excellent in vitro activities especially against methicillin-resistant Staphylococcus aureus.

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