First tricyclic oximino derivatives as 5-HT3 ligands

First tricyclic oximino derivatives as 5-HT3 ligands Further Studies on the Interaction of the 5-Hydroxytryptamine₃(5-HT₃) Receptor with Arylpiperazine Ligands. Development of a New 5-HT₃Receptor Ligand Showing Potent Acetylcholinesterase Inhibitory Properties Novel and Selective Partial Agonists of 5-HT₃ Receptors. 2. Synthesis and Biological Evaluation of Piperazinopyridopyrrolopyrazines, Piperazinopyrroloquinoxalines, and Piperazinopyridopyrroloquinoxalines Novel Potent and Selective Central 5-HT₃ Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT₃ Receptor Binding Site by Arylpiperazine Derivatives Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT₃ Receptor Agonists:  Synthesis, Further Structure−Activity Relationships, and Biological Studies Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists Novel Potent and Selective Central 5-HT₃ Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at the Central 5-HT₃ Receptors Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies Design and synthesis of novel ligands for the 5-HT3 and the 5-HT4 receptor Benzodiazepine Receptor Ligands. 7. Synthesis and Pharmacological Evaluation of New 3-Esters of the 8-Chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) Derivative:  An Anxioselective Agent in Rodents