Synthesis of metabolically blocked paclitaxel analogues

Bioorganic & Medicinal Chemistry Letters
2001.0

Abstract

The stereospecific syntheses of the metabolically blocked 6-alpha-F, Cl, Br paclitaxel, and 6-alpha-F-10-acetyldocetaxel are described and in vitro and in vivo activity is presented.

Knowledge Graph

Similar Paper