Synthesis and hypoglycemic evaluation of substituted pyrazole-4-carboxylic acids

Bioorganic & Medicinal Chemistry Letters
2002.0

Abstract

The synthesis and in vivo activities of a series of substituted pyrazole-4-carboxylic acids as hypoglycemic agents are described. Modelization of some potent compounds, comparatively to the metformine, presents certain analogies permitting to predict the design of some novel antidiabetic drugs.

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