Preparation and antidiabetic activity of some sulfonylurea derivatives of 3,5-disubstituted pyrazoles

Journal of Medicinal Chemistry
1979.0

Abstract

Four series of p-[3,5-dimethyl- (and 5-methyl-3-carboxy-) pyrazole-1]benzenesulfonylureas, thioureas, 2-thiohydantions, and 5,6-dihydro-4(3H)-oxo-2(1H)-pyrimidinethiones were prepared for evaluation as hypoglycemic agents. Biological testing of these compounds showed that some possessed antidiabetic activity.

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