Benzotrithiole 2-oxide: A new family of thiol-Activated DNA-Cleaving functionalities
Bioorganic & Medicinal Chemistry Letters
2002.0
Abstract
It was demonstrated in our studies that benzotrithiole 2-oxide was capable of causing efficient DNA cleavage in the presence of 2-mercaptoethanol or glutathione and exhibited potent cytotoxic properties against certain cancer cell lines.