Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine
Bioorganic & Medicinal Chemistry Letters
2003.0
Abstract
Combining the first generation H(1) antihistamine chlorpheniramine (1) with H(3) ligands of the alkylamine type has led to the identification of compound 9d, a dual ligand of both the H(1) and H(3) receptors.