Synthesis and antibacterial activity of oxazolidinone containing sulphonyl group

Bioorganic & Medicinal Chemistry Letters
2003.0

Abstract

A series of oxazolidinone derivatives carrying sulphonyl group was synthesized and their antibacterial activity was evaluated in vitro. Many of such compounds demonstrated potent antibacterial activity. The activity of a novel compound (YC-20) was 2-4-fold more potent than that of linezolid.

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