Synthesis and structure–activity relationships of open D-Ring galanthamine analogues

Bioorganic & Medicinal Chemistry Letters
2003.0

Abstract

Open D-ring galanthamine analogues were prepared using ring-opening reactions of the quaternarized urethane or oxazolidine functions and were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition potency.

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