Modelling of carbonic anhydrase inhibitory activity of sulfonamides using molecular negentropy

Bioorganic & Medicinal Chemistry Letters
2003.0

Abstract

The present paper deals with the modelling of carbonic anhydrase inhibitory activity of sulfonamides using molecular negentropy (N). Excellent results are obtained in multiple regression analysis upon introduction of indicator parameters. The results are critically discussed on the basis of statistical data obtained from regression analysis.

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