A novel mixed-ligand antimycobacterial dimeric copper complex of ciprofloxacin and phenanthroline

Bioorganic & Medicinal Chemistry Letters
2004.0

Abstract

A novel mixed-ligand Cu(II) complex of ciprofloxacin (cfH) and phenanthroline, is found to crystallize as a dimeric moiety containing monocationic and dicationic species. Two such dimeric moieties are found in the same unit cell leading to a dicationic cluster. The higher negative redox potential for this cluster dampens its antimycobacterial activity against M. smegmatis.

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