Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists

Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists 2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists Discovery of Potent, Nonsteroidal, and Highly Selective Glucocorticoid Receptor Antagonists Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity Synthesis and Biological Evaluation of Cyclopentaquinoline Derivatives as Nonsteroidal Glucocorticoid Receptor Antagonists Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site. Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist 11,21-Bisphenyl-19-norpregnane derivatives are selective antiglucocorticoids Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist