Aminomethyl-1,2,4-benzothiadiazines as potential analogs of .gamma.-aminobutyric acid. Unexpected discovery of a taurine antagonist

Aminomethyl-1,2,4-benzothiadiazines as potential analogs of .gamma.-aminobutyric acid. Unexpected discovery of a taurine antagonist Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1–mGAT4: Synthesis and biological evaluation (±)-2-amino-2-thiazoline-4-ethanoic acid; a novel, specific GABAA receptor agonist Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 2. Aminoalkyl derivatives New anticonvulsants: Schiff bases of .gamma.-aminobutyric acid and .gamma.-aminobutyramide 4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogs of THIP. Synthesis and biological activity High-Affinity Partial Agonist Imidazo[1,5-a]quinoxaline Amides, Carbamates, and Ureas at the γ-Aminobutyric Acid A/Benzodiazepine Receptor Complex Antiseizure Activity of Novel γ-Aminobutyric Acid (A) Receptor Subtype-Selective Benzodiazepine Analogues in Mice and Rat Models Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors