Design and synthesis of tetrahedral intermediate analogs as potential dihydroorotase inhibitors

Design and synthesis of tetrahedral intermediate analogs as potential dihydroorotase inhibitors Analogs of carbamyl aspartate as inhibitors of dihydroorotase: preparation of boronic acid transition-state analogs and a zinc chelator carbamylhomocysteine Specific Inhibition of a Family 1A Dihydroorotate Dehydrogenase by Benzoate Pyrimidine Analogues Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability Lysine and ornithine analogs of methotrexate as inhibitors of dihydrofolate reductase Analogs of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site A potent multisubstrate analog inhibitor of human thymidylate synthetase Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery Synthesis and central nervous system actions of thyrotropin-releasing hormone analog containing a dihydroorotic acid moiety