Synthesis and bacterial DNA gyrase inhibitory properties of a spirocyclopropylquinolone derivative

Synthesis and bacterial DNA gyrase inhibitory properties of a spirocyclopropylquinolone derivative Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents New "ofloxacin" type antibacterial agents. Incorporation of the spiro cyclopropyl group at N-1 Novel quinolone derivatives as potent antibacterials Synthesis and antibacterial property of quinolines with potent DNA gyrase activity Chiral DNA gyrase inhibitors. 1. Synthesis and antimicrobial activity of the enantiomers of 6-fluoro-7-(1-piperazinyl)-1-(2-trans-phenylcyclopropyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Synthesis and antibacterial activity of novel 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-4-oxoquinoline-3-carboxylic acids bearing cyclopropane-fused 2-amino-8-azabicyclo[4.3.0]nonan-8-yl substituents at the C-7 position New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay Synthesis and Structure−Activity Relationships of 2-Pyridones:  A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents New 1,4-dihydro[1,8]naphthyridine derivatives as DNA gyrase inhibitors