Structure-Activity Relationship Studies of N-Sulfonyl Analogs of Cocaine: Role of Ionic Interaction in Cocaine Binding

Structure-Activity Relationship Studies of N-Sulfonyl Analogs of Cocaine: Role of Ionic Interaction in Cocaine Binding Differential binding and dopamine uptake activity of cocaine analogues modified at nitrogen (−)-3β-Substituted Ecgonine Methyl Esters as Inhibitors for Cocaine Binding and Dopamine Uptake Synthesis, Dopamine Transporter Affinity, Dopamine Uptake Inhibition, and Locomotor Stimulant Activity of 2-Substituted 3β-Phenyltropane Derivatives Synthesis of 3-arylecgonine analogs as inhibitors of cocaine binding and dopamine uptake Synthesis and Ligand Binding Studies of 4‘-Iodobenzoyl Esters of Tropanes and Piperidines at the Dopamine Transporter Synthesis and binding affinities of 2β-(3-iodoallyloxycarbonyl)-3β-(4-substituted-aryl)tropane analogues as ligands for the dopamine transporter studies Synthesis of 8-oxa analogues of norcocaine endowed with interesting cocaine-like activity Mazindol Analogues as Potential Inhibitors of the Cocaine Binding Site at the Dopamine Transporter Methoxylation of cocaine reduces binding affinity and produces compounds of differential binding and dopamine uptake inhibitory activity: discovery of a weak cocaine "antagonist"