Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine

Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors Inhibition of Cytokine Production by Hymenialdisine Derivatives Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues Synthesis and evaluation of novel anti-proliferative pyrroloazepinone and indoloazepinone oximes derived from the marine natural product hymenialdisine Aldisine Alkaloids from the Philippine Sponge <i>Stylissa </i><i>m</i><i>assa</i> Are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1) Aldisine Alkaloids from the Philippine Sponge <i>Stylissa </i><i>m</i><i>assa</i> Are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1) 1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyano- pyrazi-2-yl)ureas as Potent and Selective Inhibitors of Chk1 Kinase:  Synthesis, Preliminary SAR, and Biological Activities Fused-azepinones: Emerging scaffolds of medicinal importance Design, Synthesis, and Biological Activity of 5,10-Dihydro-dibenzo[b,e][1,4]diazepin-11-one-Based Potent and Selective Chk-1 Inhibitors