Bioactive fluorinated derivative of amphotericin B

Bioactive fluorinated derivative of amphotericin B Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method Design, Synthesis, and Structure–Activity Relationship Studies of Bisamide Derivatives of Amphotericin B with Potent Efficacy and Low Toxicity Synthesis and biological evaluation of non-polyene analogs of amphotericin B Novel fluorinated antifolates. Enzyme inhibition and cytotoxicity studies on 2'- and 3'-fluoroaminopterin Novel alkylated azoles as potent antifungals Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase Stereoselective synthesis of 7α- and 7β-aminocholestanol as potent fungicidal drugs Possible conformation of amphotericin B dimer in membrane-bound assembly as deduced from solid-state NMR