Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720 Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors Stereochemistry–activity relationship of orally active tetralin S1P agonist prodrugs Design, Synthesis, and Antileukemic Activity of Stereochemically Defined Constrained Analogues of FTY720 (Gilenya) NBD-labeled derivatives of the immunomodulatory drug FTY720 as tools for metabolism and mode of action studies Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720 Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors