Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles

Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor Synthesis and bioactive evaluation of novel hybrids of metronidazole and berberine as new type of antimicrobial agents and their transportation behavior by human serum albumin Synthesis and biological evaluation of novel hygromycin A antibacterial agents Synthesis and SAR of novel conformationally restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 2: Amino substitutions on heterocyclic D-ring system Berberine azoles as antimicrobial agents: synthesis, biological evaluation and their interactions with human serum albumin Semisynthetic modification of hygromycin A. 2. synthesis and antibacterial activity of aryl analogs. Structure–activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors Discovery of bisindolyl-substituted cycloalkane-anellated indoles as novel class of antibacterial agents against S. aureus and MRSA Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials