Semisynthetic modification of hygromycin A. 2. synthesis and antibacterial activity of aryl analogs.
Bioorganic & Medicinal Chemistry Letters
1993.0
Abstract
Syntheses of analogs exploring the SAR of the aryl region of hygromycin A are described. Antibacterial activities against Serpulina (Treponema) hyodysenteriae and Pasteurella multocida, two key animal health pathogens, are reported.