Design, synthesis and structure–activity study of shorter hexa peptide analogues as HIV-1 protease inhibitors

Design, synthesis and structure–activity study of shorter hexa peptide analogues as HIV-1 protease inhibitors Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P₂ Ligands: Structure−Activity Studies and Biological Evaluation 4862F, a New Inhibitor of HIV-1 Protease, from the Culture of Streptomyces I03A-04862 Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure Reduction of Peptide Character of HIV Protease Inhibitors That Exhibit Nanomolar Potency against Multidrug Resistant HIV-1 Strains Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2′ side chains Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X-ray Studies Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus