Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus

Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2′ side chains Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X-ray Studies Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains A new class of anti-HIV agents: Synthesis and activity of conjugates of HIV protease inhibitors with a reverse transcriptase inhibitor Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance Design and synthesis of highly potent HIV-1 protease inhibitors with novel isosorbide-derived P2 ligands